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TIRAP Antikörper

TIRAP Reaktivität: Human, Maus, Ratte WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6292427
  • Target Alle TIRAP Antikörper anzeigen
    TIRAP (Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP))
    Reaktivität
    • 62
    • 17
    • 11
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 58
    • 3
    • 1
    Kaninchen
    Klonalität
    • 59
    • 3
    Polyklonal
    Konjugat
    • 27
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser TIRAP Antikörper ist unkonjugiert
    Applikation
    • 35
    • 26
    • 26
    • 20
    • 13
    • 11
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant protein of human TIRAP
    Isotyp
    IgG
    Top Product
    Discover our top product TIRAP Primärantikörper
  • Applikationshinweise
    WB 1:500 - 1:2000
    IHC 1:50 - 1:200
    IF 1:50 - 1:200
    Kommentare

    Highly expressed in liver, kidney, spleen, skeletal muscle and heart, Also detected in peripheral blood leukocytes, lung, placenta, small intestine, thymus, colon and brain

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20C. Avoid freeze / thaw cycles.
  • Target
    TIRAP (Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP))
    Andere Bezeichnung
    TIRAP (TIRAP Produkte)
    Synonyme
    mal antikoerper, wyatt antikoerper, BACTS1 antikoerper, Mal antikoerper, MyD88-2 antikoerper, AA407980 antikoerper, C130027E04Rik antikoerper, Tlr4ap antikoerper, Wyatt antikoerper, toll-interleukin 1 receptor (TIR) domain containing adaptor protein antikoerper, TIR domain containing adaptor protein antikoerper, toll-interleukin 1 receptor (TIR) domain containing adaptor protein L homeolog antikoerper, toll-interleukin 1 receptor (TIR) domain-containing adaptor protein antikoerper, tirap antikoerper, TIRAP antikoerper, tirap.L antikoerper, Tirap antikoerper
    Hintergrund
    The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants, however, not all variants have been fully described.
    Molekulargewicht
    23.883 kDa
    Gen-ID
    114609
    UniProt
    P58753
    Pathways
    TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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