PHLDA2 Antikörper

Produktnummer ABIN6292224

Produktdetails anti-PHLDA2 Antikörper

Target: PHLDA2 (Pleckstrin Homology-Like Domain, Family A, Member 2 (PHLDA2))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PHLDA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human PHLDA2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000
IHC 1:50 - 1:200

Kommentare:

Expressed in placenta and adult prostate gland, In placenta, it is present in all cells of the villous cytotrophoblast, The protein is absent in cells from hydatidiform moles, Hydatidiform mole is a gestation characterized by abnormal development of both fetus and trophoblast, The majority of hydatidiform moles are associated with an excess of paternal to maternal genomes and are likely to result from the abnormal expression of imprinted genes (at protein level), Expressed at low levels in adult liver and lung, and fetal liver, Expressed in adult brain and neuroblastoma, medullablastoma and glioblastoma cell lines

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20C. Avoid freeze / thaw cycles.

Details zu PHLDA2

Target: PHLDA2 (Pleckstrin Homology-Like Domain, Family A, Member 2 (PHLDA2))

Andere Bezeichnung: PHLDA2 (PHLDA2 Produkte)

Synonyme: PHLDA2 antikoerper, ipl antikoerper, phlda2 antikoerper, BRW1C antikoerper, BWR1C antikoerper, HLDA2 antikoerper, IPL antikoerper, TSSC3 antikoerper, Ipl antikoerper, Tssc3 antikoerper, zgc:110459 antikoerper, pleckstrin homology like domain family A member 2 antikoerper, Pleckstrin homology-like domain family A member 2 antikoerper, pleckstrin homology like domain, family A, member 2 antikoerper, pleckstrin homology-like domain, family A, member 2 antikoerper, pleckstrin homology-like domain, family A, member 2 L homeolog antikoerper, PHLDA2 antikoerper, phla2 antikoerper, Phlda2 antikoerper, phlda2.L antikoerper, phlda2 antikoerper

Hintergrund: This gene is located in a cluster of imprinted genes on chromosome 11p15.5, which is considered to be an important tumor suppressor gene region. Alterations in this region may be associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene has been shown to be imprinted, with preferential expression from the maternal allele in placenta and liver.

Molekulargewicht: 17.092 kDa

Gen-ID: 7262

UniProt: Q53GA4

Pathways: Regulation of Carbohydrate Metabolic Process