PRKAB2 Antikörper

Produktnummer ABIN6291758

Produktdetails anti-PRKAB2 Antikörper

Target: PRKAB2 (Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRKAB2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human PRKAB2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20C. Avoid freeze / thaw cycles.

Details zu PRKAB2

Target: PRKAB2 (Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2))

Andere Bezeichnung: PRKAB2 (PRKAB2 Produkte)

Synonyme: prkab2 antikoerper, MGC64365 antikoerper, PRKAB2 antikoerper, DKFZp469M1118 antikoerper, 5730553K21Rik antikoerper, AW049591 antikoerper, BB124140 antikoerper, protein kinase, AMP-activated, beta 2 non-catalytic subunit L homeolog antikoerper, protein kinase AMP-activated non-catalytic subunit beta 2 antikoerper, protein kinase, AMP-activated, beta 2 non-catalytic subunit antikoerper, prkab2.L antikoerper, PRKAB2 antikoerper, prkab2 antikoerper, Prkab2 antikoerper

Hintergrund: The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene.

Molekulargewicht: 30.302 kDa

Gen-ID: 5565

UniProt: O43741

Pathways: AMPK Signaling, Warburg Effekt