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WISP3 Antikörper

WISP3 Reaktivität: Human, Ratte, Maus WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6291067
  • Target Alle WISP3 Antikörper anzeigen
    WISP3 (Wnt1 Inducible Signaling Pathway Protein 3 (WISP3))
    Reaktivität
    Human, Ratte, Maus
    Wirt
    • 39
    • 1
    Kaninchen
    Klonalität
    • 40
    Polyklonal
    Konjugat
    • 11
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser WISP3 Antikörper ist unkonjugiert
    Applikation
    • 30
    • 16
    • 13
    • 13
    • 9
    • 5
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant protein of human WISP3
    Isotyp
    IgG
    Top Product
    Discover our top product WISP3 Primärantikörper
  • Applikationshinweise
    WB 1:500 - 1:2000
    Kommentare

    Predominant expression in adult kidney and testis and fetal kidney, Weaker expression found in placenta, ovary, prostate and small intestine, Also expressed in skeletally-derived cells such as synoviocytes and articular cartilage chondrocytes

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20C. Avoid freeze / thaw cycles.
  • Target
    WISP3 (Wnt1 Inducible Signaling Pathway Protein 3 (WISP3))
    Andere Bezeichnung
    WISP3 (WISP3 Produkte)
    Synonyme
    CCN6 antikoerper, LIBC antikoerper, PPAC antikoerper, PPD antikoerper, ENSMUSG00000062074 antikoerper, Gm735 antikoerper, WISP-3 antikoerper, RGD1564120 antikoerper, WISP3 antikoerper, si:dkey-119m7.6 antikoerper, WNT1 inducible signaling pathway protein 3 antikoerper, WISP3 antikoerper, Wisp3 antikoerper, wisp3 antikoerper
    Hintergrund
    This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. This gene is overexpressed in colon tumors. It may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Mutations of this gene are associated with progressive pseudorheumatoid dysplasia, an autosomal recessive skeletal disorder, indicating that the gene is essential for normal postnatal skeletal growth and cartilage homeostasis. Multiple transcript variants encoding different isoforms have been found for this gene.
    Molekulargewicht
    39.293 kDa
    Gen-ID
    8838
    UniProt
    O95389
    Pathways
    WNT Signalweg, Growth Factor Binding
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