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SMAD7 Antikörper

SMAD7 Reaktivität: Maus, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6290931
  • Target Alle SMAD7 Antikörper anzeigen
    SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))
    Reaktivität
    • 46
    • 26
    • 24
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Maus, Ratte
    Wirt
    • 39
    • 7
    Kaninchen
    Klonalität
    • 40
    • 6
    Polyklonal
    Konjugat
    • 29
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SMAD7 Antikörper ist unkonjugiert
    Applikation
    • 26
    • 17
    • 14
    • 14
    • 10
    • 8
    • 8
    • 4
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    Affinity purification
    Immunogen
    A synthetic peptide of human SMAD7
    Isotyp
    IgG
    Top Product
    Discover our top product SMAD7 Primärantikörper
  • Applikationshinweise
    WB 1:500 - 1:2000
    Kommentare

    Ubiquitous with higher expression in the lung and vascular endothelium

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20C. Avoid freeze / thaw cycles.
  • Target
    SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))
    Andere Bezeichnung
    SMAD7 (SMAD7 Produkte)
    Synonyme
    CRCS3 antikoerper, MADH7 antikoerper, MADH8 antikoerper, Smad7a antikoerper, Madh7 antikoerper, Smad10 antikoerper, madh7 antikoerper, xsmad7 antikoerper, wu:fj60c10 antikoerper, SMAD family member 7 antikoerper, SMAD family member 7 L homeolog antikoerper, SMAD7 antikoerper, Smad7 antikoerper, smad7.L antikoerper, smad7 antikoerper
    Hintergrund
    The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene.
    Molekulargewicht
    46.426 kDa
    Gen-ID
    4092
    UniProt
    O15105
    Pathways
    Interferon-gamma Pathway, Cell-Cell Junction Organization
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