SMAD7 Antikörper
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- Target Alle SMAD7 Antikörper anzeigen
- SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))
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Reaktivität
- Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SMAD7 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- Affinity purification
- Immunogen
- A synthetic peptide of human SMAD7
- Isotyp
- IgG
- Top Product
- Discover our top product SMAD7 Primärantikörper
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- Applikationshinweise
- WB 1:500 - 1:2000
- Kommentare
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Ubiquitous with higher expression in the lung and vascular endothelium
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20C. Avoid freeze / thaw cycles.
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- Target
- SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))
- Andere Bezeichnung
- SMAD7 (SMAD7 Produkte)
- Synonyme
- CRCS3 antikoerper, MADH7 antikoerper, MADH8 antikoerper, Smad7a antikoerper, Madh7 antikoerper, Smad10 antikoerper, madh7 antikoerper, xsmad7 antikoerper, wu:fj60c10 antikoerper, SMAD family member 7 antikoerper, SMAD family member 7 L homeolog antikoerper, SMAD7 antikoerper, Smad7 antikoerper, smad7.L antikoerper, smad7 antikoerper
- Hintergrund
- The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene.
- Molekulargewicht
- 46.426 kDa
- Gen-ID
- 4092
- UniProt
- O15105
- Pathways
- Interferon-gamma Pathway, Cell-Cell Junction Organization
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