LDLR Antikörper

Produktnummer ABIN6290562

Produktdetails anti-LDLR Antikörper

Target: LDLR (Low Density Lipoprotein Receptor (LDLR))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LDLR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide of human LDLR

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20C. Avoid freeze / thaw cycles.

Details zu LDLR

Target: LDLR (Low Density Lipoprotein Receptor (LDLR))

Andere Bezeichnung: LDLR (LDLR Produkte)

Synonyme: FH antikoerper, FHC antikoerper, LDLCQ2 antikoerper, Hlb301 antikoerper, LDLRA antikoerper, LDLA antikoerper, LDL receptor-2 antikoerper, fhc antikoerper, ldlcq2 antikoerper, ldlr antikoerper, ldlr2-a antikoerper, LDL receptor 1 antikoerper, ldlr-a antikoerper, ldlr-b antikoerper, low density lipoprotein receptor antikoerper, low density lipoprotein receptor a antikoerper, low density lipoprotein receptor S homeolog antikoerper, low density lipoprotein receptor L homeolog antikoerper, LDLR antikoerper, Ldlr antikoerper, ldlra antikoerper, ldlr.S antikoerper, ldlr.L antikoerper

Hintergrund: The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants.

Molekulargewicht: 95.376 kDa

Gen-ID: 3949

UniProt: P01130

Pathways: Hepatitis C, Lipid Metabolism