PKC Antikörper (AA 600-680)

Produktnummer ABIN6284619

Produktdetails anti-PKC Antikörper

Target: PKC (PKC pan) (Protein Kinase C (pan) (PKC pan))

Bindungsspezifität: AA 600-680

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PKC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: PKC is a protein encoded by the PRKCA gene which is approximately 76,7 kDa. PKC is localised to the cytoplasm and cell membrane. It is involved in RET signalling, DAG and IP3 signalling, the IL-2 Pathway, fMLP pathway and CDK-mediated phosphorylation and removal of Cdc6. It is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. It plays a role in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. PKC is expressed in the liver, blood, nervous system, skin and pancreas. Mutations in the PRKCA gene may result in glioma and myotonic dystrophy. STJ95117 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of PKC protein.

Spezifität: PKC Polyclonal Antibody detects endogenous levels of PKC protein.

Produktmerkmale: Rabbit polyclonal to PKC.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human PKC around the non-phosphorylation site of T497.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:5000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C, and avoid repeat freeze-thaw cycles.

Details zu PKC

Target: PKC (PKC pan) (Protein Kinase C (pan) (PKC pan))

Andere Bezeichnung: PKC (PKC pan Produkte)

Synonyme: PKC antikoerper, PKCI antikoerper, Prkc antikoerper, Prkcc antikoerper, RATPKCI antikoerper, protein kinase C, gamma antikoerper, Prkcg antikoerper

Molekulargewicht: 85 kDa

Gen-ID: 5578

UniProt: P17252

Pathways: Positive Regulation of Response to DNA Damage Stimulus