PPP1CA Antikörper (pThr320)

Produktnummer ABIN6282675

Produktdetails anti-PPP1CA Antikörper

Target: PPP1CA (Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA))

Bindungsspezifität: AA 260-340, pThr320

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPP1CA Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: PP1α is a protein encoded by the PPP1CA gene which is approximately 37,5 kDa. PP1α is localised to the cytoplasm and nucleus. It is involved in vascular smooth muscle contraction, regulation of lipid metabolism and insulin signalling-generic cascades. It is one of the three catalytic subunits of protein phosphatase 1. It is an enzyme that catalyses the removal of phosphate groups from serine and/or threonine residues by hydrolysis of phosphoric acid monoesters. They oppose the action of kinases and phosphorylases and are involved in signal transduction. PP1α is expressed in the lung, muscle, blood, pancreas and liver. Increased activity of this protein has been observed in the end stage of heart failure. STJ91134 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This primary antibody specifically binds to endogenous PP1α protein which only binds about T320 when T320 is phosphorylated.

Spezifität: Phospho-PP1α (T320) Polyclonal Antibody detects endogenous levels of PP1α protein only when phosphorylated at T320.

Produktmerkmale: Rabbit polyclonal to Phospho-PP1α (T320).

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human PP1alpha around the phosphorylation site of T320.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:100-1:300
ELISA 1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C, and avoid repeat freeze-thaw cycles.

Details zu PPP1CA

Target: PPP1CA (Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA))

Andere Bezeichnung: PP1alpha (PPP1CA Produkte)

Synonyme: PP-1A antikoerper, PP1A antikoerper, PP1alpha antikoerper, PPP1A antikoerper, Ppp1c antikoerper, dism2 antikoerper, ppp1a antikoerper, wu:fc04c08 antikoerper, wu:fc09b07 antikoerper, wu:fc30g11 antikoerper, wu:fe05h08 antikoerper, zgc:85729 antikoerper, Ppp1ca antikoerper, fb18b03 antikoerper, fd20h04 antikoerper, wu:fb18b03 antikoerper, wu:fd20h04 antikoerper, wu:fl22a03 antikoerper, zgc:55744 antikoerper, zgc:76940 antikoerper, protein phosphatase 1 catalytic subunit alpha antikoerper, protein phosphatase 1, catalytic subunit, alpha isoform antikoerper, protein phosphatase 1, catalytic subunit, alpha isozyme L homeolog antikoerper, protein phosphatase 1, catalytic subunit, alpha isozyme antikoerper, protein phosphatase 1, catalytic subunit, alpha isozyme a antikoerper, protein phosphatase 1, catalytic subunit, alpha isozyme b antikoerper, PPP1CA antikoerper, Ppp1ca antikoerper, ppp1ca.L antikoerper, ppp1ca antikoerper, ppp1caa antikoerper, ppp1cab antikoerper

Molekulargewicht: 37 kDa

Gen-ID: 5499

UniProt: P62136

Pathways: M Phase, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Lipid Metabolism