ADRB3 Antikörper (Internal Region)
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- Target Alle ADRB3 Antikörper anzeigen
- ADRB3 (Adrenergic, beta-3-, Receptor (ADRB3))
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Bindungsspezifität
- AA 220-300, Internal Region
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Reaktivität
- Human, Ratte, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ADRB3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Verwendungszweck
- AR-β3 is a protein encoded by the ADRB3 gene which is approximately 43,5 kDa. AR-β3 is localised to the cell membrane. It is involved in peptide ligand-binding receptors, activation of cAMP-dependent PKA, signalling by GPCR and DAG and IP3 signalling. It mediates catecholamine-induced activation of adenylate cyclase through the action of G proteins and is involved in the regulation of lipolysis and thermogenesis. AR-β3 is expressed mainly in adipose tissue. Mutations in the ADRB3 gene may be involved in diabetes mellitus and obesity. STJ91728 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of AR-β3 protein.
- Spezifität
- AR-β3 Polyclonal Antibody detects endogenous levels of AR-β3 protein.
- Produktmerkmale
- Rabbit polyclonal to AR-β3.
- Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogen
- Synthesized peptide derived from human AR-beta3
- Isotyp
- IgG
- Top Product
- Discover our top product ADRB3 Primärantikörper
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- Applikationshinweise
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WB 1:500-1:2000
ELISA 1:20000 - Kommentare
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Expressed mainly in adipose tissues.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- Target
- ADRB3 (Adrenergic, beta-3-, Receptor (ADRB3))
- Andere Bezeichnung
- AR-beta3 (ADRB3 Produkte)
- Synonyme
- BETA3AR antikoerper, Adrb-3 antikoerper, ADRB antikoerper, BAR3 antikoerper, B3AR antikoerper, GPCR antikoerper, im:7154935 antikoerper, si:ch211-215f19.1 antikoerper, zgc:194843 antikoerper, zgc:194852 antikoerper, adrenoceptor beta 3 antikoerper, adrenergic receptor, beta 3 antikoerper, adrenoceptor beta 3a antikoerper, adrenoceptor beta 3b antikoerper, ADRB3 antikoerper, Adrb3 antikoerper, adrb3a antikoerper, adrb3b antikoerper
- Molekulargewicht
- 36 kDa
- Gen-ID
- 155
- UniProt
- P13945
- Pathways
- cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, Brown Fat Cell Differentiation
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