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ARFGAP1 Antikörper (Internal Region)

ARFGAP1 Reaktivität: Human, Maus, Ratte WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6274818
  • Target Alle ARFGAP1 Antikörper anzeigen
    ARFGAP1 (ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1))
    Bindungsspezifität
    • 14
    • 10
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 44
    • 19
    • 11
    • 7
    • 4
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 40
    • 3
    • 1
    Kaninchen
    Klonalität
    • 40
    • 3
    Polyklonal
    Konjugat
    • 27
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ARFGAP1 Antikörper ist unkonjugiert
    Applikation
    • 36
    • 24
    • 22
    • 7
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    ARFGAP1 Antibody detects endogenous levels of total ARFGAP1.
    Homologie
    Rabbit
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human ARFGAP1, corresponding to a region within the internal amino acids.
    Isotyp
    IgG
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  • Applikationshinweise
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    ARFGAP1 (ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1))
    Andere Bezeichnung
    ARFGAP1 (ARFGAP1 Produkte)
    Synonyme
    ARF1GAP antikoerper, HRIHFB2281 antikoerper, AI115377 antikoerper, Arf1gap antikoerper, Arf GAP1 antikoerper, arf1gap antikoerper, atfb1 antikoerper, atfb3 antikoerper, jlns1 antikoerper, k(v)7.1 antikoerper, kcna8 antikoerper, kcna9 antikoerper, kv1.9 antikoerper, kv7.1 antikoerper, kvlqt1 antikoerper, lqt antikoerper, lqt1 antikoerper, rws antikoerper, sqt2 antikoerper, wrs antikoerper, ARFGAP3 antikoerper, ADP ribosylation factor GTPase activating protein 1 antikoerper, ADP-ribosylation factor GTPase activating protein 1 antikoerper, ADP ribosylation factor GTPase activating protein 1 S homeolog antikoerper, putative ADP-ribosylation factor GTPase activating protein 1 antikoerper, ATP-dependent RNA helicase DBP9 antikoerper, ARFGAP1 antikoerper, Arfgap1 antikoerper, arfgap1.S antikoerper, Tb11.01.6060 antikoerper, arfgap1 antikoerper, LMJF_32_1230 antikoerper, MGYG_02419 antikoerper
    Hintergrund

    Description: GTPase-activating protein (GAP) for the ADP ribosylation factor 1 (ARF1). Involved in membrane trafficking and /or vesicle transport. Promotes hydrolysis of the ARF1-bound GTP and thus, is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles, a prerequisite for vesicle's fusion with target compartment. Probably regulates ARF1-mediated transport via its interaction with the KDELR proteins and TMED2. Overexpression induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, as when ARF1 is deactivated. Its activity is stimulated by phosphoinosides and inhibited by phosphatidylcholine (By similarity).

    Gene: ARFGAP1

    Molekulargewicht
    60/48 kDa
    Gen-ID
    55738
    UniProt
    Q8N6T3
    Pathways
    p53 Signalweg, ER-Nucleus Signaling, Unfolded Protein Response
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