MCM4 Antikörper (Minichromosome Maintenance Deficient 4) (pSer88)

Details for Product anti-MCM4 Antibody No. ABIN6270001
Target
Bindungsspezifität
pSer88
14
9
7
7
5
5
4
4
3
2
2
2
2
2
2
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte
90
53
34
10
10
9
9
7
6
5
5
4
3
3
Wirt
Kaninchen
83
5
2
Klonalität
Polyklonal
Konjugat
Dieser MCM4 Antikörper ist unkonjugiert
7
4
4
4
2
2
2
2
2
2
2
2
1
1
1
1
1
Applikation
ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
67
37
36
13
13
7
3
2
2
1
1
Optionen
Immunogen A synthesized peptide derived from human MCM4 around the phosphorylation site of Ser88
Isotyp IgG
Spezifität Phospho-MCM4 (Ser88) Antibody detects endogenous levels of MCM4 only when phosphorylated at Ser88
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Andere Bezeichnung MCM4 (MCM4 Antibody Abstract)
Hintergrund

Description: Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.

Gene: MCM4

Molekulargewicht 97kDa
Gen-ID 4173
UniProt P33991
Pathways DNA Reparatur, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
Applikations-hinweise WB 1:500-1:2000, IHC 1:50-1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-Minichromosome Maintenance Deficient 4 (MCM4) (pSer88) antibody (ABIN6270001) ABIN6270002 at 1/100 staining rat kidney tissue sections by IHC-P. The tissue was for...
Image no. 2 for anti-Minichromosome Maintenance Deficient 4 (MCM4) (pSer88) antibody (ABIN6270001) Western blot analysis of Phospho-MCM4 (Ser88) in lysates of COS7 nocodazole 1ug/ml 16...