TYK2 Antikörper (Tyrosine Kinase 2) (pTyr433)

Details for Product anti-TYK2 Antibody No. ABIN6269989
Target
Bindungsspezifität
pTyr433
22
16
11
10
7
5
4
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus
109
62
44
5
3
2
1
1
1
Wirt
Kaninchen
100
9
Klonalität
Polyklonal
Konjugat
Dieser TYK2 Antikörper ist unkonjugiert
7
7
5
4
3
3
3
3
3
2
2
2
2
2
2
2
2
Applikation
ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
57
47
34
26
16
15
9
3
3
2
1
1
Optionen
Immunogen A synthesized peptide derived from human TYK2 around the phosphorylation site of Tyr433
Isotyp IgG
Spezifität Phospho-TYK2 (Tyr433) Antibody detects endogenous levels of TYK2 only when phosphorylated at Tyr433
Kreuzreaktivität Human, Maus
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Andere Bezeichnung TYK2 (TYK2 Antibody Abstract)
Hintergrund

Description: Probably involved in intracellular signal transduction by being involved in the initiation of type I IFN signaling. Phosphorylates the interferon-alpha/beta receptor alpha chain.

Gene: TYK2

Molekulargewicht 140kDa
Gen-ID 7297
UniProt P29597
Pathways JAK-STAT Signalweg, Hepatitis C
Applikations-hinweise WB 1:500-1:2000, IHC 1:50-1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-Tyrosine Kinase 2 (TYK2) (pTyr433) antibody (ABIN6269989) ABIN6269990 at 1/100 staining human kidney tissue sections by IHC-P. The tissue was f...
Image no. 2 for anti-Tyrosine Kinase 2 (TYK2) (pTyr433) antibody (ABIN6269989) ABIN6269990 at 1/100 staining human liver tissue sections by IHC-P. The tissue was fo...
Image no. 3 for anti-Tyrosine Kinase 2 (TYK2) (pTyr433) antibody (ABIN6269989) Western blot analysis of Phospho-TYK2 (Tyr433) in lysates of 293 heat shock, using Ph...