EIF4B Antikörper (Eukaryotic Translation Initiation Factor 4B) (pThr420)

Details for Product anti-EIF4B Antibody No. ABIN6269947
Target
Bindungsspezifität
pThr420
17
12
12
9
8
8
7
7
7
4
4
4
4
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus
155
71
34
7
6
4
4
3
3
3
2
1
1
Wirt
Kaninchen
133
21
1
Klonalität
Polyklonal
Konjugat
Dieser EIF4B Antikörper ist unkonjugiert
13
10
8
6
6
6
5
5
5
4
4
4
1
1
1
1
1
Applikation
ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
112
73
65
21
19
12
7
6
6
4
3
1
Optionen
Immunogen A synthesized peptide derived from human eIF4B around the phosphorylation site of Thr420
Isotyp IgG
Spezifität Phospho-eIF4B (Thr420) Antibody detects endogenous levels of eIF4B only when phosphorylated at Thr420
Kreuzreaktivität Human, Maus
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Andere Bezeichnung eIF4B (EIF4B Antibody Abstract)
Hintergrund

Description: Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.

Gene: EIF4B

Molekulargewicht 80kDa
Gen-ID 1975
UniProt P23588
Applikations-hinweise WB 1:500-1:2000, IHC 1:50-1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-Eukaryotic Translation Initiation Factor 4B (EIF4B) (pThr420) antibody (ABIN6269947) ABIN6269948 at 1/100 staining human gastric cancer tissue sections by IHC-P. The tiss...
Image no. 2 for anti-Eukaryotic Translation Initiation Factor 4B (EIF4B) (pThr420) antibody (ABIN6269947) Western blot analysis of Phospho-eIF4B (Thr420) in lysates of NIH-3T3, using Phospho-...