Filamin A Antikörper (Filamin A, alpha) (pTyr1604)

Details for Product anti-FLNA Antibody No. ABIN6269929
Target
Bindungsspezifität
pTyr1604
15
15
15
13
8
7
6
4
4
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte
144
98
96
3
3
1
1
Wirt
Kaninchen
129
14
1
Klonalität
Polyklonal
Konjugat
Dieser Filamin A Antikörper ist unkonjugiert
10
8
7
7
7
7
7
7
6
4
4
4
4
4
1
1
1
Applikation
ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
55
53
43
39
31
12
9
9
7
2
2
1
1
1
Optionen
Immunogen A synthesized peptide derived from human Filamin A around the phosphorylation site of Tyr1604
Isotyp IgG
Spezifität Phospho-Filamin A (Tyr1604) Antibody detects endogenous levels of Filamin A only when phosphorylated at Tyr1604
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Andere Bezeichnung Filamin A (FLNA Antibody Abstract)
Hintergrund

Description: Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface-localized furin, modulates its rate of internalization and directs its intracellular trafficking (By similarity). Involved in ciliogenesis. Plays a role in cell-cell contacts and adherens junctions during the development of blood vessels, heart and brain organs. Plays a role in platelets morphology through interaction with SYK that regulates ITAM- and ITAM-like-containing receptor signaling, resulting in by platelet cytoskeleton organization maintenance (By similarity).

Gene: FLNA

Molekulargewicht 280kDa
Gen-ID 2316
UniProt P21333
Pathways T-Zell Rezeptor Signalweg, Maintenance of Protein Location
Applikations-hinweise WB 1:500-1:2000, IHC 1:50-1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-Filamin A, alpha (FLNA) (pTyr1604) antibody (ABIN6269929) Western blot analysis of Phospho-Filamin A (Tyr1604) in lysates of 293, using Phospho...
Image no. 2 for anti-Filamin A, alpha (FLNA) (pTyr1604) antibody (ABIN6269929) ABIN6269930 at 1/100 staining human kidney tissue sections by IHC-P. The tissue was f...