EIF2B4 Antikörper (Eukaryotic Translation Initiation Factor 2B, Subunit 4 Delta, 67kDa) (pTyr298)

Details for Product anti-EIF2B4 Antibody No. ABIN6269923
Target
Bindungsspezifität
pTyr298
10
9
8
8
8
7
7
2
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte
64
34
16
3
3
1
1
1
Wirt
Kaninchen
57
7
Klonalität
Polyklonal
Konjugat
Dieser EIF2B4 Antikörper ist unkonjugiert
7
4
3
3
3
3
3
3
3
3
3
3
Applikation
ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
41
29
24
4
4
2
2
1
1
Optionen
Immunogen A synthesized peptide derived from human eIF2B around the phosphorylation site of Tyr298
Isotyp IgG
Spezifität Phospho-eIF2B (Tyr298) Antibody detects endogenous levels of eIF2B only when phosphorylated at Tyr298
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Andere Bezeichnung eIF2B (EIF2B4 Antibody Abstract)
Hintergrund

Description: eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.

Gene: EIF2S2

Molekulargewicht 40kDa
Gen-ID 8894
UniProt P20042
Pathways Methionine Biosynthetic Process
Applikations-hinweise WB 1:500-1:2000, IHC 1:50-1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-Eukaryotic Translation Initiation Factor 2B, Subunit 4 Delta, 67kDa (EIF2B4) (pTyr298) antibody (ABIN6269923) Western blot analysis of Phospho-eIF2B (Tyr298) in lysates of Jurkat?, using Phospho-...
Image no. 2 for anti-Eukaryotic Translation Initiation Factor 2B, Subunit 4 Delta, 67kDa (EIF2B4) (pTyr298) antibody (ABIN6269923) ABIN6269924 at 1/100 staining mouse kidney tissue sections by IHC-P. The tissue was f...
Image no. 3 for anti-Eukaryotic Translation Initiation Factor 2B, Subunit 4 Delta, 67kDa (EIF2B4) (pTyr298) antibody (ABIN6269923) ABIN6269924 at 1/100 staining human liver tissue sections by IHC-P. The tissue was fo...