AFT1 Antikörper (Activating Transcription Factor 1) (pSer198)

Details for Product anti-AFT1 Antibody No. ABIN6269917
Target
Bindungsspezifität
pSer198
22
17
9
9
7
7
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte
125
68
34
11
8
7
7
6
4
3
2
2
2
1
Wirt
Kaninchen
111
14
2
2
Klonalität
Polyklonal
Konjugat
Dieser AFT1 Antikörper ist unkonjugiert
7
5
4
4
4
4
4
3
3
2
2
2
1
1
1
1
1
1
Applikation
ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
94
49
39
23
21
16
14
10
8
4
1
1
1
Optionen
Immunogen A synthesized peptide derived from human ATF1 around the phosphorylation site of Ser198
Isotyp IgG
Spezifität Phospho-ATF1 (Ser198) Antibody detects endogenous levels of ATF1 only when phosphorylated at Ser198
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Andere Bezeichnung ATF1 (AFT1 Antibody Abstract)
Hintergrund

Description: This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation.

Gene: ATF1

Molekulargewicht 29kDa
Gen-ID 466
UniProt P18846
Pathways Neurotrophin Signalübertragung, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades
Applikations-hinweise WB 1:500-1:2000, IHC 1:50-1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-Activating Transcription Factor 1 (AFT1) (pSer198) antibody (ABIN6269917) Western blot analysis of Phospho-ATF1 (Ser198) in lysates of HT29 Insulin 0.01U/ML 15...