Phospholipase C gamma 2 Antikörper (PLCG2) (pTyr1245)

Details for Product anti-PLCG2 Antibody No. ABIN6269889
Target
Bindungsspezifität
pTyr1245
24
21
17
15
10
7
5
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte
152
124
120
9
4
4
4
4
3
1
Wirt
Kaninchen
144
8
Klonalität
Polyklonal
Konjugat
Dieser Phospholipase C gamma 2 Antikörper ist unkonjugiert
7
7
6
6
6
6
6
4
3
3
3
3
3
3
1
1
Applikation
ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
92
41
40
39
29
18
12
10
8
3
2
1
1
Optionen
Immunogen A synthesized peptide derived from human PLC 2 around the phosphorylation site of Tyr1245
Isotyp IgG
Spezifität Phospho-PLC 2 (Tyr1245) Antibody detects endogenous levels of PLC 2 only when phosphorylated at Tyr1245
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Andere Bezeichnung PLCgamma2 (PLCG2 Antibody Abstract)
Hintergrund

Description: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling.

Gene: PLCG2

Molekulargewicht 150kDa
Gen-ID 5336
UniProt P16885
Pathways RTK Signalweg, WNT Signalweg, Fc-epsilon Rezeptor Signalübertragung, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades, VEGF Signaling
Applikations-hinweise WB 1:500-1:2000, IHC 1:50-1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-Phospholipase C gamma 2 (PLCG2) (pTyr1245) antibody (ABIN6269889) ABIN6269890 at 1/100 staining human liver tissue sections by IHC-P. The tissue was fo...
Image no. 2 for anti-Phospholipase C gamma 2 (PLCG2) (pTyr1245) antibody (ABIN6269889) ABIN6269890 at 1/100 staining mouse heart tissue sections by IHC-P. The tissue was fo...
Image no. 3 for anti-Phospholipase C gamma 2 (PLCG2) (pTyr1245) antibody (ABIN6269889) Western blot analysis of Phospho-PLC 2 (Tyr1245) in lysates of HepG2 , using Phospho-...