CREB1 Antikörper (cAMP Responsive Element Binding Protein 1) (pThr100)

Details for Product anti-CREB1 Antibody No. ABIN6269885
Target
Bindungsspezifität
pThr100
67
27
21
21
18
15
15
10
9
8
8
7
6
6
5
4
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte
342
232
210
36
28
26
25
20
16
15
12
10
8
6
4
4
1
1
1
1
1
Wirt
Kaninchen
287
53
7
1
Klonalität
Polyklonal
Konjugat
Dieser CREB1 Antikörper ist unkonjugiert
23
13
12
12
11
9
9
9
9
7
6
5
3
3
3
3
3
1
Applikation
ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
245
129
124
65
55
45
43
26
23
12
10
9
3
2
2
2
1
1
Optionen
Immunogen A synthesized peptide derived from human CREB around the phosphorylation site of Thr100
Isotyp IgG
Spezifität Phospho-CREB (Thr100) Antibody detects endogenous levels of CREB only when phosphorylated at Thr100
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Andere Bezeichnung CREB (CREB1 Antibody Abstract)
Hintergrund

Description: Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.

Gene: CREB1

Molekulargewicht 43kDa
Gen-ID 1385
UniProt P16220
Pathways TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Thyroid Hormone Synthesis, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Regulation of Cell Size, Toll-Like Receptors Cascades, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Positive Regulation of fat Cell Differentiation
Applikations-hinweise WB 1:500-1:2000, IHC 1:50-1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-cAMP Responsive Element Binding Protein 1 (CREB1) (pThr100) antibody (ABIN6269885) ABIN6269886 at 1/100 staining rat kidney tissue sections by IHC-P. The tissue was for...
Image no. 2 for anti-cAMP Responsive Element Binding Protein 1 (CREB1) (pThr100) antibody (ABIN6269885) ABIN6269886 at 1/100 staining human brain tissue sections by IHC-P. The tissue was fo...
Image no. 3 for anti-cAMP Responsive Element Binding Protein 1 (CREB1) (pThr100) antibody (ABIN6269885) ABIN6269886 at 1/100 staining mouse heart tissue sections by IHC-P. The tissue was fo...
Image no. 4 for anti-cAMP Responsive Element Binding Protein 1 (CREB1) (pThr100) antibody (ABIN6269885) Western blot analysis of Phospho-CREB (Thr100) in lysates of HeLa , using Phospho-CRE...