IFNGR1 Antikörper (Interferon gamma Receptor 1) (pTyr457)

Details for Product anti-IFNGR1 Antibody No. ABIN6269881
Target
Bindungsspezifität
pTyr457
14
11
8
8
6
6
6
6
4
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte
97
45
20
7
4
Wirt
Kaninchen
81
21
12
6
1
Klonalität
Polyklonal
Konjugat
Dieser IFNGR1 Antikörper ist unkonjugiert
12
10
8
7
3
3
3
3
2
2
2
2
Applikation
ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
83
52
36
28
12
9
7
6
6
5
4
3
2
1
1
1
Optionen
Immunogen A synthesized peptide derived from human Interferon-gamma Receptor 1 around the phosphorylation site of Tyr457
Isotyp IgG
Spezifität Phospho-Interferon-γ Receptor 1 (Tyr457) Antibody detects endogenous levels of Interferon-gamma Receptor 1 only when phosphorylated at Tyr457
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Andere Bezeichnung Interferon-gamma Receptor 1 (IFNGR1 Antibody Abstract)
Hintergrund

Description: Associates with IFNGR2 to form a receptor for the cytokine interferon gamma (IFNG) (PubMed:7615558, PubMed:2971451, PubMed:7617032, PubMed:10986460). Ligand binding stimulates activation of the JAK/STAT signaling pathway (PubMed:7673114). Plays an essential role in the IFN-gamma pathway that is required for the cellular response to infectious agents (PubMed:20015550).

Gene: IFNGR1

Molekulargewicht 83kDa
Gen-ID 3459
UniProt P15260
Pathways Interferon-gamma Pathway
Applikations-hinweise WB 1:500-1:2000, IHC 1:50-1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-Interferon gamma Receptor 1 (IFNGR1) (pTyr457) antibody (ABIN6269881) ABIN6269882 at 1/100 staining mouse lung tissue sections by IHC-P. The tissue was for...
Image no. 2 for anti-Interferon gamma Receptor 1 (IFNGR1) (pTyr457) antibody (ABIN6269881) ABIN6269882 at 1/100 staining human gastric cancer tissue sections by IHC-P. The tiss...
Image no. 3 for anti-Interferon gamma Receptor 1 (IFNGR1) (pTyr457) antibody (ABIN6269881) ABIN6269882 at 1/100 staining rat kidney tissue sections by IHC-P. The tissue was for...
Image no. 4 for anti-Interferon gamma Receptor 1 (IFNGR1) (pTyr457) antibody (ABIN6269881) ABIN6269882 at 1/100 staining rat lung tissue sections by IHC-P. The tissue was forma...
Image no. 5 for anti-Interferon gamma Receptor 1 (IFNGR1) (pTyr457) antibody (ABIN6269881) Western blot analysis of Phospho-Interferon Receptor (Tyr457) in lysates of COS7, us...