E-cadherin Antikörper (Cadherin 1, Type 1, E-Cadherin (Epithelial)) (pTyr754)

Details for Product anti-CDH1 Antibody No. ABIN6269849
Target
Bindungsspezifität
pTyr754
20
16
16
15
15
15
10
9
8
7
6
6
4
4
4
4
4
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte
314
144
130
25
15
14
9
8
8
6
6
6
4
3
3
3
3
3
3
2
1
Wirt
Kaninchen
222
113
14
3
2
Klonalität
Polyklonal
Konjugat
Dieser E-cadherin Antikörper ist unkonjugiert
35
29
12
11
10
8
8
7
7
7
7
6
3
3
3
3
3
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
255
122
114
95
67
59
52
39
38
21
13
13
10
8
6
5
5
5
3
1
1
Optionen
Immunogen A synthesized peptide derived from human CDH1 around the phosphorylation site of Tyr754
Isotyp IgG
Spezifität Phospho-CDH1 (Tyr754) Antibody detects endogenous levels of CDH1 only when phosphorylated at Tyr754
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Andere Bezeichnung CDH1 (CDH1 Antibody Abstract)
Hintergrund

Description: Cadherins are calcium-dependent cell adhesion proteins (PubMed:11976333). They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells (PubMed:11976333). Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.

Gene: CDH1

Molekulargewicht 120kDa
Gen-ID 999
UniProt P12830
Pathways Sensory Perception of Sound, Cell-Cell Junction Organization, Tube Formation
Applikations-hinweise WB 1:500-1:2000, IHC 1:50-1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (pTyr754) antibody (ABIN6269849) ABIN6269850 at 1/100 staining mouse lung tissue sections by IHC-P. The tissue was for...
Image no. 2 for anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (pTyr754) antibody (ABIN6269849) ABIN6269850 at 1/100 staining human kidney tissue sections by IHC-P. The tissue was f...
Image no. 3 for anti-Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (pTyr754) antibody (ABIN6269849) Western blot analysis of extracts of Mouse brain tissue sample,using Phospho-CDH1 (Ty...