CD79a Molecule, Immunoglobulin-Associated alpha (CD79A) (pTyr199) Antikörper

Details zu Produkt Nr. ABIN6269847
Target
Bindungsspezifität
pTyr199
103
32
12
9
9
8
7
7
7
7
5
4
4
3
3
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte
260
146
117
68
67
54
29
27
27
27
19
8
3
3
3
3
3
2
1
Wirt
Kaninchen
147
131
1
Klonalität
Polyklonal
Konjugat
Unkonjugiert
20
17
13
13
8
6
6
6
6
6
6
6
6
6
6
6
6
6
6
4
3
2
2
2
2
1
1
Applikation
ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
168
126
117
72
67
49
36
17
12
5
5
3
2
2
1
1
1
1
Optionen
Immunogen A synthesized peptide derived from human CD79A around the phosphorylation site of Tyr199
Isotyp IgG
Spezifität Phospho-CD79A (Tyr199) Antibody detects endogenous levels of CD79A only when phosphorylated at Tyr199
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Andere Bezeichnung CD79A (CD79A Antibody Abstract)
Hintergrund

Description: Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells.

Gene: CD79A

Molekulargewicht 25kDa
Gen-ID 973
UniProt P11912
Applikations-hinweise WB 1:500-1:2000, IHC 1:50-1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-CD79a Molecule, Immunoglobulin-Associated alpha (CD79A) (pTyr199) antibody (ABIN6269847) Western blot analysis of Phospho-CD79A (Tyr199) in lysates of HuvEc, using Phospho-CD...
Image no. 2 for anti-CD79a Molecule, Immunoglobulin-Associated alpha (CD79A) (pTyr199) antibody (ABIN6269847) ABIN6269848 at 1/100 staining human brain tissue sections by IHC-P. The tissue was fo...