KRT18 Antikörper (Keratin 18) (pTyr13)

Details for Product anti-KRT18 Antibody No. ABIN6269801
Target
Bindungsspezifität
pTyr13
25
16
15
15
14
11
8
7
6
6
5
4
4
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte
343
136
130
63
42
40
39
34
31
26
25
22
22
22
9
9
8
7
4
3
2
2
2
1
1
Wirt
Kaninchen
184
180
7
7
4
2
1
Klonalität
Polyklonal
Konjugat
Dieser KRT18 Antikörper ist unkonjugiert
31
22
9
9
9
9
9
9
9
4
4
4
4
4
4
4
4
4
4
4
4
4
3
3
3
3
3
2
2
1
1
1
Applikation
ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
251
145
130
126
95
78
59
48
41
28
24
14
12
10
9
9
2
1
Optionen
Immunogen A synthesized peptide derived from human Keratin 18 around the phosphorylation site of Tyr13
Isotyp IgG
Spezifität Phospho-Keratin 18 (Tyr13) Antibody detects endogenous levels of Keratin 18 only when phosphorylated at Tyr13
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Andere Bezeichnung Keratin 18 (KRT18 Antibody Abstract)
Hintergrund

Description: Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.

Gene: KRT18

Molekulargewicht 46kDa
Gen-ID 3875
UniProt P05783
Pathways Apoptose, Caspase Kaskade in der Apoptose
Applikations-hinweise WB 1:500-1:2000, IHC 1:50-1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-Keratin 18 (KRT18) (pTyr13) antibody (ABIN6269801) Western blot analysis of Phospho-Keratin 18 (Tyr13) in lysates of HT29, using Phospho...