EIF2A Antikörper (Eukaryotic Translation Initiation Factor 2A, 65kDa) (pTyr150)

Details for Product anti-EIF2A Antibody No. ABIN6269791
Target
Bindungsspezifität
pTyr150
13
12
12
10
9
8
8
7
5
4
4
3
3
2
2
2
2
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte
106
61
60
7
5
3
2
2
1
1
1
1
1
1
Wirt
Kaninchen
89
18
Klonalität
Polyklonal
Konjugat
Dieser EIF2A Antikörper ist unkonjugiert
7
5
5
5
4
4
3
3
3
2
2
2
2
2
2
2
2
Applikation
ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
71
49
40
25
20
16
13
4
3
1
1
Optionen
Immunogen A synthesized peptide derived from human eIF2 alpha around the phosphorylation site of Tyr150
Isotyp IgG
Spezifität Phospho-eIF2 alpha (Tyr150) Antibody detects endogenous levels of eIF2 alpha only when phosphorylated at Tyr150
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Andere Bezeichnung eIF2 alpha (EIF2A Antibody Abstract)
Hintergrund

Description: Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S pre-initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.

Gene: EIF2S1

Molekulargewicht 38kDa
Gen-ID 1965
UniProt P05198
Pathways Ribonucleoprotein Complex Subunit Organization, ER-Nucleus Signaling, Hepatitis C, Methionine Biosynthetic Process, Ribosome Assembly
Applikations-hinweise WB 1:500-1:2000, IHC 1:50-1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A) (pTyr150) antibody (ABIN6269791) ABIN6269792 at 1/100 staining mouse brain tissue sections by IHC-P. The tissue was fo...
Image no. 2 for anti-Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A) (pTyr150) antibody (ABIN6269791) ABIN6269792 at 1/100 staining rat heart tissue sections by IHC-P. The tissue was form...
Image no. 3 for anti-Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A) (pTyr150) antibody (ABIN6269791) ABIN6269792 at 1/100 staining human kidney tissue sections by IHC-P. The tissue was f...
Image no. 4 for anti-Eukaryotic Translation Initiation Factor 2A, 65kDa (EIF2A) (pTyr150) antibody (ABIN6269791) Western blot analysis of Phospho-eIF2 alpha (Tyr150) in lysates of K562 IFN 1000U/ml ...