Myelin Protein Zero-Like 1 (MPZL1) (pTyr260) Antikörper

Details zu Produkt Nr. ABIN6269751
Target
Bindungsspezifität
pTyr260
9
8
7
5
4
2
1
1
1
Reaktivität
Human, Maus
48
13
13
3
3
3
2
2
1
Wirt
Kaninchen
45
3
Klonalität
Polyklonal
Konjugat
Unkonjugiert
5
4
4
4
4
4
4
1
1
Applikation
ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
24
13
7
5
4
1
1
Optionen
Immunogen A synthesized peptide derived from human PZR around the phosphorylation site of Tyr260
Isotyp IgG
Spezifität Phospho-PZR (Tyr260) Antibody detects endogenous levels of PZR only when phosphorylated at Tyr260
Kreuzreaktivität Human, Maus
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Andere Bezeichnung PZR (MPZL1 Antibody Abstract)
Hintergrund

Description: Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 3 seems to have a dominant negative role, it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility.

Gene: MPZL1

Molekulargewicht 29kDa
Gen-ID 9019
UniProt O95297
Applikations-hinweise WB 1:500-1:2000, IHC 1:50-1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-Myelin Protein Zero-Like 1 (MPZL1) (pTyr260) antibody (ABIN6269751) Western blot analysis of Phospho-PZR (Tyr260) in lysates of HepG2?, using Phospho-PZR...
Image no. 2 for anti-Myelin Protein Zero-Like 1 (MPZL1) (pTyr260) antibody (ABIN6269751) ABIN6269752 at 1/100 staining human kidney tissue sections by IHC-P. The tissue was f...
Image no. 3 for anti-Myelin Protein Zero-Like 1 (MPZL1) (pTyr260) antibody (ABIN6269751) ABIN6269752 at 1/100 staining mouse liver tissue sections by IHC-P. The tissue was fo...