NFAT5 Antikörper (Nuclear Factor of Activated T-Cells 5, Tonicity-Responsive) (pSer145)

Details for Product anti-NFAT5 Antibody No. ABIN6269741
Target
Bindungsspezifität
pSer145
18
9
8
7
6
5
3
2
2
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus
84
70
35
3
2
2
2
2
1
1
Wirt
Kaninchen
81
4
Klonalität
Polyklonal
Konjugat
Dieser NFAT5 Antikörper ist unkonjugiert
7
6
5
5
5
5
5
3
3
2
2
2
2
2
Applikation
ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
30
28
26
15
10
4
3
2
Optionen
Immunogen A synthesized peptide derived from human NFAT5/TonEBP around the phosphorylation site of Ser145
Isotyp IgG
Spezifität Phospho-NFAT5/TonEBP (Ser145) Antibody detects endogenous levels of NFAT5/TonEBP only when phosphorylated at Ser145
Kreuzreaktivität Human, Maus
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Andere Bezeichnung NFAT5/TonEBP (NFAT5 Antibody Abstract)
Hintergrund

Description: Transcription factor involved, among others, in the transcriptional regulation of osmoprotective and inflammatory genes. Mediates the transcriptional response to hypertonicity (PubMed:10051678). Positively regulates the transcription of LCN2 and S100A4 genes, optimal transactivation of these genes requires the presence of DDX5/DDX17 (PubMed:22266867). Binds the DNA consensus sequence 5'-[ACT][AG]TGGAAA[CAT]A[TA][ATC][CA][ATG][GT][GAC][CG][CT]-3' (PubMed:10377394).

Gene: NFAT5

Molekulargewicht 160kDa
Gen-ID 10725
UniProt O94916
Pathways RTK Signalweg, WNT Signalweg
Applikations-hinweise WB 1:500-1:2000, IHC 1:50-1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-Nuclear Factor of Activated T-Cells 5, Tonicity-Responsive (NFAT5) (pSer145) antibody (ABIN6269741) ABIN6269742 at 1/100 staining human kidney tissue sections by IHC-P. The tissue was f...
Image no. 2 for anti-Nuclear Factor of Activated T-Cells 5, Tonicity-Responsive (NFAT5) (pSer145) antibody (ABIN6269741) Western blot analysis of Phospho-NFAT5/TonEBP (Ser145) in lysates of HepG2, using Pho...