RAD17 Homolog (S. Pombe) (RAD17) (pSer359) Antikörper

Details zu Produkt Nr. ABIN6269737
Target
Bindungsspezifität
pSer359
21
9
9
9
8
8
8
7
5
4
4
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte
130
76
51
5
5
4
4
2
2
1
1
1
1
Wirt
Kaninchen
127
7
2
1
Klonalität
Polyklonal
Konjugat
Unkonjugiert
10
7
5
5
5
5
5
5
5
2
2
2
2
2
2
2
2
Applikation
ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
95
47
26
23
23
14
12
6
4
2
1
1
1
Optionen
Immunogen A synthesized peptide derived from human RAD17 around the phosphorylation site of Ser359
Isotyp IgG
Spezifität Phospho-RAD17 (Ser359) Antibody detects endogenous levels of RAD17 only when phosphorylated at Ser359
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Andere Bezeichnung RAD17 (RAD17 Antibody Abstract)
Hintergrund

Description: Essential for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage. Has a weak ATPase activity required for binding to chromatin. Participates in the recruitment of the RAD1-RAD9-HUS1 complex and RHNO1 onto chromatin, and in CHEK1 activation. May also serve as a sensor of DNA replication progression, and may be involved in homologous recombination.

Gene: RAD17

Molekulargewicht 77kDa
Gen-ID 5884
UniProt O75943
Applikations-hinweise WB 1:500-1:2000, IHC 1:50-1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-RAD17 Homolog (S. Pombe) (RAD17) (pSer359) antibody (ABIN6269737) ABIN6269738 at 1/100 staining rat lung tissue sections by IHC-P. The tissue was forma...
Image no. 2 for anti-RAD17 Homolog (S. Pombe) (RAD17) (pSer359) antibody (ABIN6269737) ABIN6269738 at 1/100 staining human lung tissue sections by IHC-P. The tissue was for...
Image no. 3 for anti-RAD17 Homolog (S. Pombe) (RAD17) (pSer359) antibody (ABIN6269737) Western blot analysis of Phospho-RAD17 (Ser359) in lysates of HeLa , using Phospho-RA...