ATG13 Antikörper (Autophagy Related 13) (pThr24) Primary Antibody
ATG13
Reaktivität: Human, Maus, Ratte
ELISA, WB
Wirt: Kaninchen
Polyclonal
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Produktnummer ABIN6269705
$450.00
Zzgl. Versandkosten $45.00
local_shipping
Lieferung nach:
Vereinigte Staaten von Amerika
Lieferung in 11 bis 12 Werktagen
-
- Target
- Bindungsspezifität
- pThr24
- Reaktivität
- Human, Maus, Ratte
- Wirt
- Kaninchen
- Klonalität
- Polyklonal
- Konjugat
- Dieser ATG13 Antikörper ist unkonjugiert
- Applikation
- ELISA, Western Blotting (WB)
- Spezifität
- Phospho-Atg13 (Thr24) Antibody detects endogenous levels of Atg13 only when phosphorylated at Thr24
- Kreuzreaktivität
- Human, Maus, Ratte (Rattus)
- Aufreinigung
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
- Immunogen
- A synthesized peptide derived from human Atg13 around the phosphorylation site of Thr24
- Isotyp
- IgG
-
-
- Applikationshinweise
- WB 1:500-1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C.Stable for 12 months from date of receipt
- Haltbarkeit
- 12 months
-
- Target
- Andere Bezeichnung
- Atg13 (ATG13 Antibody Abstract)
- Synonyme
- zgc:63526, KIAA0652, PARATARG8, 1110053A20Rik, D2Ertd391e, Harbi1, Harbi1l, RGD1310685, autophagy related 13, ATG13 autophagy related 13 homolog (S. cerevisiae), ATG13, atg13, Atg13
- Hintergrund
Description: Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.
Gene: ATG13
- Molekulargewicht
- 57kDa
- Gen-ID
- 9776
- UniProt
- O75143
- Pathways
- PI3K-Akt Signalweg, Autophagie
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