Catenin (Cadherin-Associated Protein), delta 1 (CTNND1) (pTyr280) Antikörper

Details zu Produkt Nr. ABIN6269689
Target
Bindungsspezifität
pTyr280
25
22
17
15
15
8
8
8
8
7
6
4
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte
194
126
124
5
5
5
5
4
4
3
1
1
Wirt
Kaninchen
162
33
Klonalität
Polyklonal
Konjugat
Unkonjugiert
15
12
9
9
9
9
9
7
7
5
5
5
5
5
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
85
67
48
47
38
29
28
14
13
5
2
2
1
Optionen
Immunogen A synthesized peptide derived from human CTNND1 around the phosphorylation site of Tyr280
Isotyp IgG
Spezifität Phospho-CTNND1 (Tyr280) Antibody detects endogenous levels of CTNND1 only when phosphorylated at Tyr280
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Andere Bezeichnung CTNND1 (CTNND1 Antibody Abstract)
Hintergrund

Description: Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity). Associates with and regulates the cell adhesion properties of both C-, E- and N-cadherins, being critical for their surface stability. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.

Gene: CTNND1

Molekulargewicht 105kDa
Gen-ID 1500
UniProt O60716
Pathways EGFR Signaling Pathway, Neurotrophin Signalübertragung, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling
Applikations-hinweise WB 1:500-1:2000, IHC 1:50-1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-Catenin (Cadherin-Associated Protein), delta 1 (CTNND1) (pTyr280) antibody (ABIN6269689) ABIN6269690 at 1/100 staining human kidney tissue sections by IHC-P. The tissue was f...
Image no. 2 for anti-Catenin (Cadherin-Associated Protein), delta 1 (CTNND1) (pTyr280) antibody (ABIN6269689) ABIN6269690 at 1/100 staining mouse brain tissue sections by IHC-P. The tissue was fo...
Image no. 3 for anti-Catenin (Cadherin-Associated Protein), delta 1 (CTNND1) (pTyr280) antibody (ABIN6269689) Western blot analysis of Phospho-CTNND1 (Tyr280) in lysates of HuvEc, using Phospho-C...