Doublecortin Antikörper (DCX) (pSer332)

Details for Product anti-DCX Antibody No. ABIN6269671
Target
Bindungsspezifität
pSer332
9
8
8
7
7
5
4
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte
119
77
65
5
5
4
2
2
2
1
1
1
1
1
Wirt
Kaninchen
100
19
9
2
Klonalität
Polyklonal
Konjugat
Dieser Doublecortin Antikörper ist unkonjugiert
10
6
5
5
5
5
5
4
4
2
2
2
Applikation
ELISA, Western Blotting (WB)
95
65
38
17
16
16
15
7
5
2
1
1
1
1
Optionen
Immunogen A synthesized peptide derived from human Doublecortin around the phosphorylation site of Ser332
Isotyp IgG
Spezifität Phospho-Doublecortin (Ser332) Antibody detects endogenous levels of Doublecortin only when phosphorylated at Ser332
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Andere Bezeichnung Doublecortin (DCX Antibody Abstract)
Hintergrund

Description: Microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCLK1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with PAFAH1B1/LIS-1 of overlapping, but distinct, signaling pathways that promote neuronal migration.

Gene: DCX

Molekulargewicht 49.3kDa
Gen-ID 1641
UniProt O43602
Applikations-hinweise WB 1:500-1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-Doublecortin (DCX) (pSer332) antibody (ABIN6269671) Western blot analysis of extracts of Mouse brain? tissue sample,using Phospho-Doublec...