PPP1R12A Antikörper (Myosin Phosphatase, Target Subunit 1) (pSer509)

Produktnummer ABIN6269627

Produktdetails anti-PPP1R12A Antikörper

Target:

PPP1R12A

Bindungsspezifität: pSer509

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPP1R12A Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Spezifität: Phospho-MYPT1 (Ser509) Antibody detects endogenous levels of MYPT1 only when phosphorylated at Ser509

Kreuzreaktivität: Human, Maus, Ratte (Rattus)

Aufreinigung: The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Immunogen: A synthesized peptide derived from human MYPT1 around the phosphorylation site of Ser509

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C.Stable for 12 months from date of receipt

Haltbarkeit: 12 months

Details zu PPP1R12A

Target:

PPP1R12A

Andere Bezeichnung: MYPT1 (PPP1R12A Antibody Abstract)

Hintergrund:

Description: Key regulator of protein phosphatase 1C (PPP1C). Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Capable of inhibiting HIF1AN-dependent suppression of HIF1A activity.

Gene: PPP1R12A

Molekulargewicht: 115kDa

Gen-ID: 4659

UniProt: O14974

Pathways: M Phase