Lipin 1 (LPIN1) (pThr14) Antikörper

Details zu Produkt Nr. ABIN6269587
Target
Bindungsspezifität
pThr14
15
9
7
3
3
3
2
2
2
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte
52
51
48
3
2
2
2
1
1
1
1
1
1
1
1
Wirt
Kaninchen
72
9
9
Klonalität
Polyklonal
Konjugat
Unkonjugiert
6
6
6
6
5
5
5
3
3
2
2
2
2
2
1
1
1
Applikation
ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
37
30
26
16
14
4
4
4
3
1
1
1
1
1
Optionen
Immunogen A synthesized peptide derived from human LPIN1 around the phosphorylation site of Thr14
Isotyp IgG
Spezifität Phospho-LPIN1(Thr14) Antibody detects endogenous levels of LPIN1 only when phosphorylated at Thr14
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Andere Bezeichnung LPIN1 (LPIN1 Antibody Abstract)
Hintergrund

Description: Plays important roles in controlling the metabolism of fatty acids at different levels. Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis in the reticulum endoplasmic membrane. Acts also as a nuclear transcriptional coactivator for PPARGC1A/PPARA to modulate lipid metabolism gene expression (By similarity). Is involved in adipocyte differentiation. May also be involved in mitochondrial fission by converting phosphatidic acid to diacylglycerol (By similarity).

Gene: LPIN1

Molekulargewicht 99kDa
Gen-ID 23175
UniProt Q14693
Pathways Monocarboxylic Acid Catabolic Process
Applikations-hinweise WB 1:500-1:2000, IHC 1:50-1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-Lipin 1 (LPIN1) (pThr14) antibody (ABIN6269587) Western blot analysis of Phospho-LPIN1(Thr14) in lysates of K562?, using Phospho-LPIN...
Image no. 2 for anti-Lipin 1 (LPIN1) (pThr14) antibody (ABIN6269587) ABIN6269588 at 1/100 staining human kidney tissue sections by IHC-P. The tissue was f...
Image no. 3 for anti-Lipin 1 (LPIN1) (pThr14) antibody (ABIN6269587) ABIN6269588 at 1/100 staining rat kidney tissue sections by IHC-P. The tissue was for...
Image no. 4 for anti-Lipin 1 (LPIN1) (pThr14) antibody (ABIN6269587) ABIN6269588 at 1/100 staining mouse kidney tissue sections by IHC-P. The tissue was f...