Transcription Factor AP-2 gamma (Activating Enhancer Binding Protein 2 Gamma) (TFAP2C) (pSer434) Antikörper

Details zu Produkt Nr. ABIN6269581
Target
Bindungsspezifität
pSer434
15
12
7
5
4
4
2
2
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus
71
42
33
6
5
5
4
4
4
3
3
2
2
2
1
Wirt
Kaninchen
58
11
7
Klonalität
Polyklonal
Konjugat
Unkonjugiert
5
3
3
3
3
3
3
3
3
1
1
1
1
1
1
1
1
Applikation
ELISA, Western Blotting (WB)
40
29
25
13
7
3
2
2
1
1
1
Optionen
Immunogen A synthesized peptide derived from human TFAP2C around the phosphorylation site of Ser434
Isotyp IgG
Spezifität Phospho-TFAP2C(Ser434) Antibody detects endogenous levels of TFAP2C only when phosphorylated at Ser434
Kreuzreaktivität Human, Maus
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Andere Bezeichnung TFAP2C (TFAP2C Antibody Abstract)
Hintergrund

Description: Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.

Gene: TFAP2C

Molekulargewicht 49kDa
Gen-ID 7022
UniProt Q92754
Pathways Stem Cell Maintenance
Applikations-hinweise WB 1:500-1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-Transcription Factor AP-2 gamma (Activating Enhancer Binding Protein 2 Gamma) (TFAP2C) (pSer434) antibody (ABIN6269581) Western blot analysis of Phospho-TFAP2C(Ser434) in lysates of MCF7 , using Phospho-TF...