Thioredoxin (TXN) (pThr100) Antikörper

Details zu Produkt Nr. ABIN6269571
Target
Bindungsspezifität
pThr100
24
8
7
6
5
4
4
2
1
1
1
1
1
Reaktivität
Human, Maus, Ratte
108
45
35
10
3
3
3
2
1
1
1
1
1
Wirt
Kaninchen
110
28
1
1
Klonalität
Polyklonal
Konjugat
Unkonjugiert
19
16
6
4
3
3
3
3
3
3
3
2
1
Applikation
ELISA, Western Blotting (WB)
105
66
40
15
15
14
11
10
8
8
4
2
1
1
1
Optionen
Immunogen A synthesized peptide derived from human TXN around the phosphorylation site of Thr100
Isotyp IgG
Spezifität Phospho-TXN(Thr100) Antibody detects endogenous levels of TXN only when phosphorylated at Thr100
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Andere Bezeichnung TXN (TXN Antibody Abstract)
Hintergrund

Description: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity.

Gene: TXN

Molekulargewicht 12kDa
Gen-ID 7295
UniProt P10599
Pathways Carbohydrate Homeostasis, Cell RedoxHomeostasis
Applikations-hinweise WB 1:500-1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-Thioredoxin (TXN) (pThr100) antibody (ABIN6269571) Western blot analysis of Phospho-TXN(Thr100) in lysates of HeLa , using Phospho-TXN(T...