GLI2 Antikörper (GLI Family Zinc Finger 2) (pSer136)

Details for Product anti-GLI2 Antibody No. ABIN6269563
Target
Bindungsspezifität
pSer136
12
8
7
4
2
2
2
1
1
1
1
1
1
Reaktivität
Human
46
17
6
3
2
2
Wirt
Kaninchen
42
7
2
Klonalität
Polyklonal
Konjugat
Dieser GLI2 Antikörper ist unkonjugiert
4
3
3
3
3
3
3
1
1
1
1
1
Applikation
ELISA, Western Blotting (WB)
29
23
14
8
5
3
2
Optionen
Immunogen A synthesized peptide derived from human GLI2 around the phosphorylation site of Ser136
Isotyp IgG
Spezifität Phospho-GLI2(Ser136) Antibody detects endogenous levels of GLI2 only when phosphorylated at Ser136
Kreuzreaktivität Human
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Andere Bezeichnung GLI2 (GLI2 Antibody Abstract)
Hintergrund

Description: Functions as transcription regulator in the hedgehog (Hh) pathway (PubMed:18455992, PubMed:26565916). Functions as transcriptional activator (PubMed:9557682, PubMed:19878745, PubMed:24311597). May also function as transcriptional repressor (By similarity). Requires STK36 for full transcriptional activator activity. Required for normal embryonic development (PubMed:15994174, PubMed:20685856).

Gene: GLI2

Molekulargewicht 133kDa
Gen-ID 2736
UniProt P10070
Pathways Hedgehog Signalweg, Dopaminergic Neurogenesis
Applikations-hinweise WB 1:500-1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-GLI Family Zinc Finger 2 (GLI2) (pSer136) antibody (ABIN6269563) Western blot analysis of Phospho-GLI2(Ser136) in lysates of HeLa?, using Phospho-GLI2...