GLI1 Antikörper (Zinc Finger Protein GLI1) (pSer1071)

Details for Product anti-GLI1 Antibody No. ABIN6269559
Target
Bindungsspezifität
pSer1071
16
15
7
4
4
4
4
4
4
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus
110
65
38
4
4
4
4
4
3
2
1
Wirt
Kaninchen
92
17
3
1
1
Klonalität
Polyklonal
Konjugat
Dieser GLI1 Antikörper ist unkonjugiert
8
6
6
6
6
6
6
3
3
1
1
1
1
1
Applikation
ELISA, Western Blotting (WB)
69
31
17
13
13
7
7
5
4
2
2
1
1
1
1
1
Optionen
Immunogen A synthesized peptide derived from human GLI1 around the phosphorylation site of Ser1071
Isotyp IgG
Spezifität Phospho-GLI1(Ser1071) Antibody detects endogenous levels of GLI1 only when phosphorylated at Ser1071
Kreuzreaktivität Human, Maus
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Andere Bezeichnung GLI1 (GLI1 Antibody Abstract)
Hintergrund

Description: Acts as a transcriptional activator (PubMed:19706761, PubMed:10806483, PubMed:19878745, PubMed:24311597, PubMed:24217340). Binds to the DNA consensus sequence 5'-GACCACCCA-3' (PubMed:2105456, PubMed:8378770, PubMed:24217340). May regulate the transcription of specific genes during normal development (PubMed:19706761). May play a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling (PubMed:19706761). Plays a role in cell proliferation and differentiation via its role in SHH signaling (Probable).

Gene: GLI1

Molekulargewicht 119kDa
Gen-ID 2735
UniProt P08151
Pathways Hedgehog Signalweg, Dopaminergic Neurogenesis
Applikations-hinweise WB 1:500-1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-Zinc Finger Protein GLI1 (GLI1) (pSer1071) antibody (ABIN6269559) Western blot analysis of Phospho-GLI1(Ser1071) in lysates of PC-3, using Phospho-GLI1...