FK506 Binding Protein 4, 59kDa (FKBP4) (pTyr220) Antikörper

Details zu Produkt Nr. ABIN6269547
Target
Bindungsspezifität
pTyr220
10
10
7
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte
129
75
62
30
28
4
4
3
3
3
1
Wirt
Kaninchen
61
60
8
Klonalität
Polyklonal
Konjugat
Unkonjugiert
7
4
4
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
107
71
57
42
32
29
19
14
10
3
2
2
1
1
1
Optionen
Immunogen A synthesized peptide derived from human FKBP4 around the phosphorylation site of Tyr220
Isotyp IgG
Spezifität Phospho-FKBP4(Tyr220) Antibody detects endogenous levels of FKBP4 only when phosphorylated at Tyr220
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Andere Bezeichnung FKBP4 (FKBP4 Antibody Abstract)
Hintergrund

Description: Immunophilin protein with PPIase and co-chaperone activities. Component of steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). May play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening. Acts also as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. May have a protective role against oxidative stress in mitochondria.

Gene: FKBP4

Molekulargewicht 51kDa
Gen-ID 2288
UniProt Q02790
Pathways Intracellular Steroid Hormone Receptor Signaling Pathway
Applikations-hinweise WB 1:500-1:2000, IHC 1:50-1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-FK506 Binding Protein 4, 59kDa (FKBP4) (pTyr220) antibody (ABIN6269547) ABIN6269548 at 1/100 staining human kidney tissue sections by IHC-P. The tissue was f...
Image no. 2 for anti-FK506 Binding Protein 4, 59kDa (FKBP4) (pTyr220) antibody (ABIN6269547) ABIN6269548 at 1/100 staining rat spleen tissue sections by IHC-P. The tissue was for...
Image no. 3 for anti-FK506 Binding Protein 4, 59kDa (FKBP4) (pTyr220) antibody (ABIN6269547) ABIN6269548 at 1/100 staining mouse kidney tissue sections by IHC-P. The tissue was f...
Image no. 4 for anti-FK506 Binding Protein 4, 59kDa (FKBP4) (pTyr220) antibody (ABIN6269547) Western blot analysis of Phospho-FKBP4(Tyr220) in lysates of Jurkat, using Phospho-FK...