ZEB1 Antikörper (Zinc Finger E-Box Binding Homeobox 1) (pSer887)

Details for Product anti-ZEB1 Antibody No. ABIN6269545
Target
Bindungsspezifität
pSer887
12
7
5
4
4
4
3
2
2
2
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte
70
29
27
5
5
4
4
4
3
3
2
1
1
Wirt
Kaninchen
45
19
7
Klonalität
Polyklonal
Konjugat
Dieser ZEB1 Antikörper ist unkonjugiert
4
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Applikation
ELISA, Western Blotting (WB)
52
29
18
14
11
10
9
5
3
3
2
1
1
1
1
1
Optionen
Immunogen A synthesized peptide derived from human ZEB1 around the phosphorylation site of Ser887
Isotyp IgG
Spezifität Phospho-ZEB1(Ser887) Antibody detects endogenous levels of ZEB1 only when phosphorylated at Ser887
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Andere Bezeichnung ZEB1 (ZEB1 Antibody Abstract)
Hintergrund

Description: Acts as a transcriptional repressor. Inhibits interleukin-2 (IL-2) gene expression. Enhances or represses the promoter activity of the ATP1A1 gene depending on the quantity of cDNA and on the cell type. Represses E-cadherin promoter and induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1. Represses BCL6 transcription in the presence of the corepressor CTBP1. Positively regulates neuronal differentiation. Represses RCOR1 transcription activation during neurogenesis. Represses transcription by binding to the E box (5'-CANNTG-3'). Promotes tumorigenicity by repressing stemness-inhibiting microRNAs.

Gene: ZEB1

Molekulargewicht 124kDa
Gen-ID 6935
UniProt P37275
Pathways Regulation of Muscle Cell Differentiation
Applikations-hinweise WB 1:500-1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-Zinc Finger E-Box Binding Homeobox 1 (ZEB1) (pSer887) antibody (ABIN6269545) Western blot analysis of Phospho-ZEB1(Ser887) in lysates of HEK-293, using Phospho-ZE...