HFE2 Antikörper (Hemochromatosis Type 2 (Juvenile)) (pSer42)

Details for Product anti-HFE2 Antibody No. ABIN6269529
Target
Bindungsspezifität
pSer42
11
10
10
8
8
7
7
7
6
4
3
2
2
2
2
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte
98
45
35
2
2
1
1
1
1
Wirt
Kaninchen
87
15
Klonalität
Polyklonal
Konjugat
Dieser HFE2 Antikörper ist unkonjugiert
11
7
5
4
4
4
3
2
2
2
2
2
1
1
1
1
1
Applikation
ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
84
42
36
19
14
13
8
6
4
4
1
Optionen
Immunogen A synthesized peptide derived from human HFE2 around the phosphorylation site of Ser42
Isotyp IgG
Spezifität Phospho-HFE2(Ser42) Antibody detects endogenous levels of HFE2 only when phosphorylated at Ser42
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Andere Bezeichnung HFE2 (HFE2 Antibody Abstract)
Hintergrund

Description: Acts as a bone morphogenetic protein (BMP) coreceptor. Through enhancement of BMP signaling regulates hepcidin (HAMP) expression and regulates iron homeostasis.

Gene: HFE2

Molekulargewicht 45kDa
Gen-ID 148738
UniProt Q6ZVN8
Pathways Transition Metal Ion Homeostasis
Applikations-hinweise WB 1:500-1:2000, IHC 1:50-1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-Hemochromatosis Type 2 (Juvenile) (HFE2) (pSer42) antibody (ABIN6269529) ABIN6269530 at 1/100 staining human heart tissue sections by IHC-P. The tissue was fo...
Image no. 2 for anti-Hemochromatosis Type 2 (Juvenile) (HFE2) (pSer42) antibody (ABIN6269529) ABIN6269530 at 1/100 staining rat kidney tissue sections by IHC-P. The tissue was for...
Image no. 3 for anti-Hemochromatosis Type 2 (Juvenile) (HFE2) (pSer42) antibody (ABIN6269529) ABIN6269530 at 1/100 staining mouse kidney tissue sections by IHC-P. The tissue was f...
Image no. 4 for anti-Hemochromatosis Type 2 (Juvenile) (HFE2) (pSer42) antibody (ABIN6269529) Western blot analysis of Phospho-HFE2(Ser42) in lysates of PC3?, using Phospho-HFE2(S...