EIF4A1 Antikörper (Eukaryotic Translation Initiation Factor 4A1) (pTyr48)

Details for Product anti-EIF4A1 Antibody No. ABIN6269525
Target
Bindungsspezifität
pTyr48
7
3
3
2
2
2
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte
47
35
34
4
4
4
4
4
4
3
2
1
1
1
Wirt
Kaninchen
36
11
Klonalität
Polyklonal
Konjugat
Dieser EIF4A1 Antikörper ist unkonjugiert
3
3
3
3
3
3
3
Applikation
ELISA, Western Blotting (WB)
32
12
9
6
6
3
3
3
1
1
Optionen
Immunogen A synthesized peptide derived from human EIF4A1 around the phosphorylation site of Tyr48
Isotyp IgG
Spezifität Phospho-EIF4A1(Tyr48) Antibody detects endogenous levels of EIF4A1 only when phosphorylated at Tyr48
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Andere Bezeichnung EIF4A1 (EIF4A1 Antibody Abstract)
Hintergrund

Description: ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.

Gene: EIF4A1

Molekulargewicht 46kDa
Gen-ID 1973
UniProt P60842
Applikations-hinweise WB 1:500-1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-Eukaryotic Translation Initiation Factor 4A1 (EIF4A1) (pTyr48) antibody (ABIN6269525) Western blot analysis of Phospho-EIF4A1(Tyr48) in lysates of Jurkat?, using Phospho-E...