NOTCH3 Antikörper (Notch 3) (pSer84)

Details for Product anti-NOTCH3 Antibody No. ABIN6269513
Target
Bindungsspezifität
pSer84
30
13
8
7
4
2
2
2
1
1
1
1
Reaktivität
Human, Maus, Ratte
86
26
20
1
Wirt
Kaninchen
53
26
7
3
1
1
Klonalität
Polyklonal
Konjugat
Dieser NOTCH3 Antikörper ist unkonjugiert
8
8
6
5
5
4
3
2
2
2
2
2
1
Applikation
ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
50
42
39
15
6
4
3
2
1
1
Optionen
Immunogen A synthesized peptide derived from human NOTCH3 around the phosphorylation site of Ser84
Isotyp IgG
Spezifität Phospho-NOTCH3(Ser84) Antibody detects endogenous levels of NOTCH3 only when phosphorylated at Ser84
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Andere Bezeichnung NOTCH3 (NOTCH3 Antibody Abstract)
Hintergrund

Description: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs (By similarity).

Gene: NOTCH3

Molekulargewicht 244kDa
Gen-ID 4854
UniProt Q9UM47
Pathways Notch Signalweg
Applikations-hinweise WB 1:500-1:2000, IHC 1:50-1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-Notch 3 (NOTCH3) (pSer84) antibody (ABIN6269513) ABIN6269514 at 1/100 staining mouse kidney tissue sections by IHC-P. The tissue was f...
Image no. 2 for anti-Notch 3 (NOTCH3) (pSer84) antibody (ABIN6269513) ABIN6269514 at 1/100 staining human heart tissue sections by IHC-P. The tissue was fo...
Image no. 3 for anti-Notch 3 (NOTCH3) (pSer84) antibody (ABIN6269513) ABIN6269514 at 1/100 staining rat kidney tissue sections by IHC-P. The tissue was for...
Image no. 4 for anti-Notch 3 (NOTCH3) (pSer84) antibody (ABIN6269513) Western blot analysis of Phospho-NOTCH3(Ser84) in lysates of K562?, using Phospho-NOT...