TTF1 Antikörper (Transcription Termination Factor, RNA Polymerase I) (pSer23)

Details for Product anti-TTF1 Antibody No. ABIN6269511
Target
Bindungsspezifität
pSer23
8
8
7
4
2
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte
67
32
29
Wirt
Kaninchen
54
16
Klonalität
Polyklonal
Konjugat
Dieser TTF1 Antikörper ist unkonjugiert
4
3
3
3
3
3
3
2
2
1
1
Applikation
ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
31
26
20
20
13
8
7
7
6
3
2
2
1
Optionen
Immunogen A synthesized peptide derived from human TTF1 around the phosphorylation site of Ser23
Isotyp IgG
Spezifität Phospho-TTF1(Ser23) Antibody detects endogenous levels of TTF1 only when phosphorylated at Ser23
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Andere Bezeichnung TTF1 (TTF1 Antibody Abstract)
Hintergrund

Description: Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis. Forms a regulatory loop with GRHL2 that coordinates lung epithelial cell morphogenesis and differentiation. Activates the transcription of GNRHR and plays a role in enhancing the circadian oscillation of its gene expression. Represses the transcription of the circadian transcriptional repressor NR1D1 (By similarity).

Gene: NKX2-1

Molekulargewicht 42kDa
Gen-ID 7080
UniProt P43699
Pathways Thyroid Hormone Synthesis, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
Applikations-hinweise WB 1:500-1:2000, IHC 1:50-1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-Transcription Termination Factor, RNA Polymerase I (TTF1) (pSer23) antibody (ABIN6269511) ABIN6269512 at 1/100 staining rat lung tissue sections by IHC-P. The tissue was forma...
Image no. 2 for anti-Transcription Termination Factor, RNA Polymerase I (TTF1) (pSer23) antibody (ABIN6269511) Western blot analysis of Phospho-TTF1(Ser23) in lysates of HeLa?, using Phospho-TTF1(...
Image no. 3 for anti-Transcription Termination Factor, RNA Polymerase I (TTF1) (pSer23) antibody (ABIN6269511) ABIN6269512 at 1/100 staining mouse lung tissue sections by IHC-P. The tissue was for...
Image no. 4 for anti-Transcription Termination Factor, RNA Polymerase I (TTF1) (pSer23) antibody (ABIN6269511) ABIN6269512 at 1/100 staining human lung tissue sections by IHC-P. The tissue was for...