KISS1R Antikörper (KISS1 Receptor) (pSer368)

Details for Product anti-KISS1R Antibody No. ABIN6269495
Target
Bindungsspezifität
pSer368
15
7
6
5
3
3
2
2
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte
61
32
21
2
2
1
1
1
1
1
Wirt
Kaninchen
68
2
Klonalität
Polyklonal
Konjugat
Dieser KISS1R Antikörper ist unkonjugiert
5
4
3
3
3
3
3
1
1
1
1
1
1
1
1
1
1
Applikation
ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
26
20
19
13
13
6
4
4
4
3
2
Optionen
Immunogen A synthesized peptide derived from human KISS1R around the phosphorylation site of Ser368
Isotyp IgG
Spezifität Phospho-KISS1R(Ser368) Antibody detects endogenous levels of KISS1R only when phosphorylated at Ser368
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Andere Bezeichnung KISS1R (KISS1R Antibody Abstract)
Hintergrund

Description: Receptor for metastin (kisspeptin-54 or kp-54), a C-terminally amidated peptide of KiSS1. KiSS1 is a metastasis suppressor protein that suppresses metastases in malignant melanomas and in some breast carcinomas without affecting tumorigenicity. The metastasis suppressor properties may be mediated in part by cell cycle arrest and induction of apoptosis in malignant cells. The receptor is essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/KISS1R system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood. The receptor is also probably involved in the regulation and fine-tuning of trophoblast invasion generated by the trophoblast itself. Analysis of the transduction pathways activated by the receptor identifies coupling to phospholipase C and intracellular calcium release through pertussis toxin-insensitive G(q) proteins.

Gene: KISS1R

Molekulargewicht 43kDa
Gen-ID 84634
UniProt Q969F8
Applikations-hinweise WB 1:500-1:2000, IHC 1:50-1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-KISS1 Receptor (KISS1R) (pSer368) antibody (ABIN6269495) ABIN6269496 at 1/100 staining rat heart tissue sections by IHC-P. The tissue was form...
Image no. 2 for anti-KISS1 Receptor (KISS1R) (pSer368) antibody (ABIN6269495) Western blot analysis of Phospho-KISS1R(Ser368) in lysates of HepG2?, using Phospho-K...
Image no. 3 for anti-KISS1 Receptor (KISS1R) (pSer368) antibody (ABIN6269495) ABIN6269496 at 1/100 staining mouse kidney tissue sections by IHC-P. The tissue was f...
Image no. 4 for anti-KISS1 Receptor (KISS1R) (pSer368) antibody (ABIN6269495) ABIN6269496 at 1/100 staining human heart tissue sections by IHC-P. The tissue was fo...