GDF9 Antikörper (Growth Differentiation Factor 9) (pTyr394)

Details for Product anti-GDF9 Antibody No. ABIN6269487
Target
Bindungsspezifität
pTyr394
13
9
9
8
7
5
5
4
4
3
2
2
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte
87
32
28
2
1
1
1
1
Wirt
Kaninchen
85
6
1
1
Klonalität
Polyklonal
Konjugat
Dieser GDF9 Antikörper ist unkonjugiert
8
6
6
3
3
3
3
3
3
2
2
2
1
1
1
1
1
Applikation
ELISA, Western Blotting (WB)
65
44
39
16
13
4
3
3
2
2
Optionen
Immunogen A synthesized peptide derived from human GDF9 around the phosphorylation site of Tyr394
Isotyp IgG
Spezifität Phospho-GDF9(Tyr394) Antibody detects endogenous levels of GDF9 only when phosphorylated at Tyr394
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Andere Bezeichnung GDF9 (GDF9 Antibody Abstract)
Hintergrund

Description: Required for ovarian folliculogenesis. Promotes primordial follicle development. Stimulates granulosa cell proliferation. Promotes cell transition from G0/G1 to S and G2/M phases, through an increase of CCND1 and CCNE1 expression, and RB1 phosphorylation. It regulates STAR expression and cAMP-dependent progesterone release in granulosa and thecal cells. Attenuates the suppressive effects of activin A on STAR expression and progesterone production by increasing the expression of inhibin B. It suppresses FST and FSTL3 production in granulosa-lutein cells.

Gene: GDF9

Molekulargewicht 51kDa
Gen-ID 2661
UniProt O60383
Applikations-hinweise WB 1:500-1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-Growth Differentiation Factor 9 (GDF9) (pTyr394) antibody (ABIN6269487) Western blot analysis of Phospho-GDF9(Tyr394) in lysates of HL60?, using Phospho-GDF9...