TIMP1 Antikörper (TIMP Metallopeptidase Inhibitor 1)

Details for Product anti-TIMP1 Antibody No. ABIN6269426
Target
Reaktivität
Human, Maus, Ratte
165
73
72
19
16
12
9
4
3
2
2
2
1
1
Wirt
Kaninchen
129
65
7
6
2
Klonalität
Polyklonal
Konjugat
Dieser TIMP1 Antikörper ist unkonjugiert
29
17
11
6
6
4
4
4
4
4
4
3
3
3
3
3
2
2
2
2
Applikation
ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blotting (WB)
132
102
62
35
25
23
19
17
11
9
8
7
6
5
4
4
4
4
3
1
1
1
1
1
Optionen
Immunogen A synthesized peptide derived from human TIMP1
Isotyp IgG
Spezifität TIMP1 Antibody detects endogenous levels of total TIMP1
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
Target
Andere Bezeichnung TIMP1 (TIMP1 Antibody Abstract)
Hintergrund

Description: Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Mediates erythropoiesis in vitro, but, unlike IL3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors.

Gene: TIMP1

Molekulargewicht 24kDa
Gen-ID 7076
UniProt P01033
Applikations-hinweise WB 1:500-1:2000, IF/ICC 1:100-1:500
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) antibody (ABIN6269426) Western blot analysis of TIMP1 expression in 293 whole cell lysates,The lane on the l...
Image no. 2 for anti-TIMP Metallopeptidase Inhibitor 1 (TIMP1) antibody (ABIN6269426) ABIN6269427 staining 293 cells by IF/ICC. The sample were fixed with PFA and permeabi...