AMPA Receptor Antikörper

Details zu Produkt Nr. ABIN6268484
Target
Reaktivität
Human, Maus, Ratte
2
1
1
Wirt
Kaninchen
2
Klonalität
Polyklonal
Applikation
ELISA, Western Blotting (WB)
2
1
Optionen
Immunogen A synthesized peptide derived from human AMPA Receptor
Isotyp IgG
Spezifität AMPA Receptor Antibody detects endogenous levels of AMPA Receptor
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
Target
Hintergrund

Description: Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.

Gene: GRIA1

Molekulargewicht 102kDa
Gen-ID 2890
UniProt P42261
Applikations-hinweise WB 1:500-1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-AMPA Receptor antibody (ABIN6268484) Western blot analysis of AMPA Receptor in lysates of COLO205 , using AMPA Receptor ...