NR4A1 Antikörper (Nuclear Receptor Subfamily 4, Group A, Member 1)

Details for Product anti-NR4A1 Antibody No. ABIN6268448
Target
Reaktivität
Human, Maus, Ratte
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51
49
12
9
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6
6
4
2
2
1
1
1
1
Wirt
Kaninchen
99
8
6
Klonalität
Polyklonal
Konjugat
Dieser NR4A1 Antikörper ist unkonjugiert
7
6
4
4
4
3
3
3
3
3
3
3
1
1
1
1
1
Applikation
ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
74
43
23
17
14
12
7
4
4
2
2
1
1
1
Optionen
Immunogen A synthesized peptide derived from human Nur77
Isotyp IgG
Spezifität Nur77 Antibody detects endogenous levels of Nur77
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
Target
Andere Bezeichnung Nur77 (NR4A1 Antibody Abstract)
Hintergrund

Description: Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3' (By similarity). May inhibit NF-kappa-B transactivation of IL2. Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation.

Gene: NR4A1

Molekulargewicht 70-80kDa
Gen-ID 3164
UniProt P22736
Pathways Fc-epsilon Rezeptor Signalübertragung, Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Steroid Hormone Mediated Signaling Pathway
Applikations-hinweise WB 1:500-1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1) antibody (ABIN6268448) Western blot analysis of Nur77 in lysates of HepG2 , using Nur77 Antibody(ABIN6268449).