Aconitase 1 Antikörper (Aconitase 1, Soluble)

Details for Product anti-ACO1 Antibody No. ABIN6268446
Target
Reaktivität
Human, Maus, Ratte
69
34
33
2
2
1
1
1
1
1
1
1
1
Wirt
Kaninchen
68
4
1
Klonalität
Polyklonal
Konjugat
Dieser Aconitase 1 Antikörper ist unkonjugiert
8
4
2
2
2
2
2
2
1
Applikation
ELISA, Western Blotting (WB)
47
29
25
9
9
4
2
2
1
Optionen
Immunogen A synthesized peptide derived from human IREB1
Isotyp IgG
Spezifität IREB1 Antibody detects endogenous levels of IREB1
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
Target
Andere Bezeichnung IREB1 (ACO1 Antibody Abstract)
Hintergrund

Description: Iron sensor. Binds a 4Fe-4S cluster and functions as aconitase when cellular iron levels are high. Functions as mRNA binding protein that regulates uptake, sequestration and utilization of iron when cellular iron levels are low. Binds to iron-responsive elements (IRES) in target mRNA species when iron levels are low. Binding of a 4Fe-4S cluster precludes RNA binding.

Gene: ACO1

Molekulargewicht 98kDa
Gen-ID 48
UniProt P21399
Pathways Transition Metal Ion Homeostasis
Applikations-hinweise WB 1:500-1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-Aconitase 1, Soluble (ACO1) antibody (ABIN6268446) Western blot analysis of IREB1 in lysates of HeLa, using IREB1 Antibody(ABIN6268447).