WW and C2 Domain Containing 1 (WWC1) Antikörper

Details zu Produkt Nr. ABIN6268258
Target
Reaktivität
Human, Maus, Ratte
44
24
20
2
2
1
1
1
1
Wirt
Kaninchen
44
3
Klonalität
Polyklonal
Konjugat
Unkonjugiert
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Applikation
ELISA, Western Blotting (WB)
35
22
13
8
6
3
2
1
1
1
1
Optionen
Immunogen A synthesized peptide derived from human KIBRA
Isotyp IgG
Spezifität KIBRA Antibody detects endogenous levels of KIBRA
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
Target
Andere Bezeichnung KIBRA (WWC1 Antibody Abstract)
Hintergrund

Description: Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with NF2 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. Acts as a transcriptional coactivator of ESR1 which plays an essential role in DYNLL1-mediated ESR1 transactivation. Regulates collagen-stimulated activation of the ERK/MAPK cascade. Modulates directional migration of podocytes. Acts as a substrate for PRKCZ. Plays a role in cognition and memory performance.

Gene: WWC1

Molekulargewicht 135kDa
Gen-ID 23286
UniProt Q8IX03
Applikations-hinweise WB 1:500-1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-WW and C2 Domain Containing 1 (WWC1) antibody (ABIN6268258) Western blot analysis of KIBRA in lysates of 293, using KIBRA Antibody(ABIN6268259).