TACC3 Antikörper (Transforming, Acidic Coiled-Coil Containing Protein 3) (pSer558)

Details for Product anti-TACC3 Antibody No. ABIN6268218
Target
Bindungsspezifität
pSer558
8
4
3
3
2
2
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte
56
34
21
1
1
1
1
1
1
1
Wirt
Kaninchen
45
10
1
Klonalität
Polyklonal
Konjugat
Dieser TACC3 Antikörper ist unkonjugiert
4
3
3
3
3
3
3
1
1
Applikation
ELISA, Western Blotting (WB)
34
21
20
16
9
9
2
1
1
Optionen
Immunogen A synthesized peptide derived from human TACC3 around the phosphorylation site of Ser558
Isotyp IgG
Spezifität Phospho-TACC3 (Ser558) Antibody detects endogenous levels of TACC3 only when phosphorylated at Ser558
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Andere Bezeichnung TACC3 (TACC3 Antibody Abstract)
Hintergrund

Description: Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors (By similarity). Acts as component of the TACC3/ch-TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter-microtubule bridge. The TACC3/ch-TOG/clathrin complex is required for the maintenance of kinetochore fiber tension (PubMed:21297582, PubMed:23532825). May be involved in the control of cell growth and differentiation. May contribute to cancer (PubMed:14767476).

Gene: TACC3

Molekulargewicht 80kDa
Gen-ID 10460
UniProt Q9Y6A5
Pathways Maintenance of Protein Location
Applikations-hinweise WB 1:500-1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-Transforming, Acidic Coiled-Coil Containing Protein 3 (TACC3) (pSer558) antibody (ABIN6268218) Western blot analysis of Phospho-TACC3 (Ser558) in lysates of HeLa?, using Phospho-TA...