CARD11 Antikörper (Caspase Recruitment Domain Family, Member 11) (pSer652)

Details for Product anti-CARD11 Antibody No. ABIN6268186
Target
Bindungsspezifität
pSer652
11
5
3
2
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte
40
15
5
2
2
1
1
Wirt
Kaninchen
32
7
1
1
Klonalität
Polyklonal
Konjugat
Dieser CARD11 Antikörper ist unkonjugiert
2
1
1
1
1
1
1
1
1
1
1
1
Applikation
ELISA, Western Blotting (WB)
36
20
20
6
5
3
3
2
1
1
1
1
Optionen
Immunogen A synthesized peptide derived from human CARD11 around the phosphorylation site of Ser652
Isotyp IgG
Spezifität Phospho-CARD11 (Ser652) Antibody detects endogenous levels of CARD11 only when phosphorylated at Ser652
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Reinigung The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Target
Andere Bezeichnung CARD11 (CARD11 Antibody Abstract)
Hintergrund

Description: Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Activates NF-kappa-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10. Also activates the TORC1 signaling pathway.

Gene: CARD11

Molekulargewicht 130kDa
Gen-ID 84433
UniProt Q9BXL7
Pathways T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung
Applikations-hinweise WB 1:500-1:2000
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20 °C.Stable for 12 months from date of receipt
Haltbarkeit 12 months
Bilder
Image no. 1 for anti-Caspase Recruitment Domain Family, Member 11 (CARD11) (pSer652) antibody (ABIN6268186) Western blot analysis of Phospho-CARD11 (Ser652) in lysates of Jurkat?, using Phospho...